Article

Systematic analysis of the sphingomyelin synthase family in <i>C. elegans</i>

2023-07-25

Abstract excerpt

Sphingomyelin (SM) is a major component of mammalian cell membranes and particularly abundant in the myelin sheath that surrounds nerve fibers. Its production is catalyzed by SM synthases SMS1 and SMS2, which interconvert phosphatidylcholine and ceramide to diacylglycerol and SM in the Golgi and at the plasma membrane, respectively. As the lipids participating in this reaction fulfill both structural and signaling...

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Literature Corpus work: 0e8c95fd-2d91-5113-a66c-401a1dc94288
DOI: 10.1101/2023.07.25.550547

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