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Article

Loss of sphingomyelin synthase-1 does not cause egg retention or locomotion defects in Caenorhabditis elegans.

Biology open - 15 Mar 2026

Wang Wenyue, Gao Xiaoyan, Pocock Roger

Abstract excerpt

Sphingomyelin is a critical sphingolipid found in plasma membranes of metazoa that provides structural and communicative functions. Sphingomyelin synthases are key enzymes that generate sphingomyelin but their precise functions in animal development and function are not fully understood. The Caenorhabditis elegans model encodes five sphingomyelin synthases (sms-1-5). Previously, egg-laying and locomotion...

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Identifiers

PMID: 41783982
DOI: 10.1242/bio.062520
PMCID: PMC13054943

Genes

SMS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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