Article

Accelerated somatic mutation calling for whole-genome and whole-exome sequencing data from heterogenous tumor samples

2023-07-04

Abstract excerpt

Accurate detection of somatic mutations in DNA sequencing data is a fundamental prerequisite for cancer research. Previous analytical challenge was overcome by consensus mutation calling from four to five popular callers. This, however, increases the already nontrivial computing time from individual callers. Here, we launch MuSE2.0, powered by multi-step parallelization and efficient memory allocation, to resolve...

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Literature Corpus work: 0e71f6ae-0a77-5c8b-9df3-0de91d1cc808
DOI: 10.1101/2023.07.04.547569

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