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Article

SomaticSniper: identification of somatic point mutations in whole genome sequencing data.

Bioinformatics (Oxford, England) - 1 Feb 2012

Larson David E, Harris Christopher C, Chen Ken, Koboldt Daniel C, Abbott Travis E, Dooling David J, Ley Timothy J, Mardis Elaine R, Wilson Richard K, Ding Li

Abstract excerpt

MOTIVATION: The sequencing of tumors and their matched normals is frequently used to study the genetic composition of cancer. Despite this fact, there remains a dearth of available software tools designed to compare sequences in pairs of samples and identify sites that are likely to be unique to one sample. RESULTS: In this article, we describe the mathematical basis of our SomaticSniper software for comparing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22155872
DOI: 10.1093/bioinformatics/btr665
PMCID: PMC3268238

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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