Article
Signals from the reproductive system regulate the lifespan of C. elegans.
Nature - 27 May 1999
Hsin H, Kenyon C
Abstract excerpt
Understanding how the ageing process is regulated is a fascinating and fundamental problem in biology. Here we demonstrate that signals from the reproductive system influence the lifespan of the nematode Caenorhabditis elegans. If the cells that give rise to the germ line are killed with a laser microbeam, the lifespan of the animal is extended. Our findings suggest that germline signals act by modulating the...
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