Article

Different gametogenesis states uniquely impact longevity in <i>Caenorhabditis elegans</i>

2023-06-14

Abstract excerpt

Curtailed reproduction affects lifespan and fat metabolism in diverse organisms, suggesting a regulatory axis between these processes. In Caenorhabditis elegans , ablation of germline stem cells (GSCs) leads to extended lifespan and increased fat accumulation, suggesting GSCs emit signals that modulate systemic physiology. Previous studies mainly focused on the germline-less glp-1(e2141) mutant, however, the her...

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Literature Corpus work: dcdcf6fa-c4fd-5233-aa7e-7fb1358a1368
DOI: 10.1101/2023.06.13.544885

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