Article

Synphilin-1 as a modulator of aSyn assembly

2023-05-17

Abstract excerpt

<title>Abstract</title> <p>Alpha-synuclein (aSyn) is an intrinsically disordered protein associated with Parkinson’s disease and other synucleinopathies, where it accumulates in pathognomonic protein inclusions in the brain. However, both the physiological function and the pathological role of aSyn are still elusive. Unlike other proteins also prone to aggregation, expression of aSyn in cell models does not readi...

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Literature Corpus work: 0dd85544-b213-5267-8327-c3a2a0ed594a
DOI: 10.21203/rs.3.rs-2923196/v1

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