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Article

Alpha-synuclein at the intracellular and the extracellular side: functional and dysfunctional implications.

Biological chemistry - 1 Jan 2017

Ottolini Denis, Calí Tito, Szabò Ildikò, Brini Marisa

Abstract excerpt

Alpha-synuclein (α-syn) is an abundant neuronal protein whose physiological function, even if still not completely understood, has been consistently related to synaptic function and vesicle trafficking. A group of disorders known as synucleinopathies, among which Parkinson's disease (PD), is deeply associated with the misfolding and aggregation of α-syn, which can give rise to proteinaceous inclusion known as...

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PMID: 27508962
DOI: 10.1515/hsz-2016-0201

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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