Article

Baseline α-synuclein seeding activity and disease progression in sporadic and genetic Parkinson’s disease in the PPMI cohort

2024-09-30

Abstract excerpt

<h4>Summary</h4> <h4>Background</h4> α-Synuclein (α-syn) seed amplification assays (SAAs) have shown remarkable potential in diagnosing Parkinson’s disease (PD). Using data from the Parkinson’s Progression Markers Initiative (PPMI) cohort, we aimed to test whether baseline α-syn seeding activity was associated with disease progression in sporadic PD, LRRK2 -associated PD ( LRRK2 PD), and GBA -associated PD ( GBA P...

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Literature Corpus work: 0d86f22e-a198-5d02-b218-b81ce450e687
DOI: 10.1101/2024.09.27.24311107

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