Article

Diagnostic and prognostic value of alpha-synuclein seed amplification assay in Parkinson’s disease: a longitudinal cohort study

2024-12-05

Abstract excerpt

<h4>Summary</h4> <h4>Background</h4> Alpha-synuclein seed amplification assay (a-syn SAA) has been proposed to be a diagnostic biomarker for Parkinson’s disease (PD). Here, we have explored the diagnostic and prognostic value of cerebrospinal fluid (CSF) a-syn SAA status and seeding kinetics in PD. <h4>Methods</h4> Baseline CSF a-syn SAA data and longitudinal clinical data were collected and analysed between 1 st...

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Literature Corpus work: c7e9d29b-1bf9-50d6-b824-5ff322348f41
DOI: 10.1101/2024.12.03.24318422

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