Article

SAA positivity rate amongst dual LRRK2-GBA1, GBA1 and LRRK2 carriers with Parkinson’s disease

2026-05-27

Abstract excerpt

<h4>ABSTRACT</h4> We investigated whether people with Parkinson’s disease who are dual GBA1+LRRK2 carriers have a milder, LRRK2-like phenotype as previously reported. This was accomplished by comparing clinical features and alpha-synuclein seed amplification assay (SAA) positivity rates between dual GBA1+LRRK2-PD(n=13), GBA1-PD(n=169) and LRRK2-PD(n=175) carriers in a cross-sectional retrospective study of Parkin...

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Literature Corpus work: 4db6bce6-af26-5a18-beaf-5077dc0d890b
DOI: 10.64898/2026.05.26.26354106

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