Article

Absent from DNA and protein: genomic characterization of nullomers and nullpeptides across functional categories and evolution

2020-03-03

Abstract excerpt

Nullomers and nullpeptides are short DNA or amino acid sequences that are absent from a genome or proteome, respectively. One potential cause for their absence could be that they have a detrimental impact on an organism. Here, we identified all possible nullomers and nullpeptides in the genomes and proteomes of over thirty species and show that a significant proportion of these sequences are under negative selecti...

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Literature Corpus work: 0d52148d-6c41-50a7-9fd3-ece1257c9373
DOI: 10.1101/2020.03.02.972422

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