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Article

Nullomers: really a matter of natural selection?

PloS one - 10 Oct 2007

Acquisti Claudia, Poste George, Curtiss David, Kumar Sudhir

Abstract excerpt

BACKGROUND: Nullomers are short DNA sequences that are absent from the genomes of humans and other species. Assuming that nullomers are the signatures of natural selection against deleterious sequences in humans, the use of nullomers in drug target identification, pesticide development, environmental monitoring, and forensic applications has been envisioned. RESULTS: Here, we show that the hypermutability of CpG...

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Identifiers

PMID: 17925870
DOI: 10.1371/journal.pone.0001022
PMCID: PMC1995752

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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