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Article

Absent from DNA and protein: genomic characterization of nullomers and nullpeptides across functional categories and evolution.

Genome biology - 25 Aug 2021

Georgakopoulos-Soares Ilias, Yizhar-Barnea Ofer, Mouratidis Ioannis, Hemberg Martin, Ahituv Nadav

Abstract excerpt

Nullomers and nullpeptides are short DNA or amino acid sequences that are absent from a genome or proteome, respectively. One potential cause for their absence could be their having a detrimental impact on an organism. RESULTS: Here, we identify all possible nullomers and nullpeptides in the genomes and proteomes of thirty eukaryotes and demonstrate that a significant proportion of these sequences are under...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34433494
DOI: 10.1186/s13059-021-02459-z
PMCID: PMC8386077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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