Article

The shrinking human protein coding complement: are there now fewer than 20,000 genes?

2014-01-17

Abstract excerpt

Determining the full complement of protein-coding genes is a key goal of genome annotation. The most powerful approach for confirming protein coding potential is the detection of cellular protein expression through peptide mass spectrometry experiments. Here we map the peptides detected in 7 large-scale proteomics studies to almost 60% of the protein coding genes in the GENCODE annotation the human genome. We find...

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Literature Corpus work: b568bc5a-53a7-5bfd-a061-32c474f505ef
DOI: 10.1101/001909

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