Article
Significant non-existence of sequences in genomes and proteomes.
Nucleic acids research - 6 Apr 2021
Koulouras Grigorios, Frith Martin C
Abstract excerpt
Minimal absent words (MAWs) are minimal-length oligomers absent from a genome or proteome. Although some artificially synthesized MAWs have deleterious effects, there is still a lack of a strategy for the classification of non-occurring sequences as potentially malicious or benign. In this work, by using Markovian models with multiple-testing correction, we reveal significant absent oligomers, which are...
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