Article

Dynamic compartmentalization of the pro-invasive transcription factor NHR-67 reveals a role for Groucho in regulating a proliferative-invasive cellular switch in C. elegans

2023-12-01

Abstract excerpt

A growing body of evidence suggests that cell division and basement membrane invasion are mutually exclusive cellular behaviors. How cells switch between proliferative and invasive states is not well understood. Here, we investigated this dichotomy in vivo by examining two cell types in the developing Caenorhabditis elegans somatic gonad that derive from equipotent progenitors, but exhibit distinct cell behaviors:...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0d152f52-f51c-5b87-bbf6-b60ac0fe1ea7
DOI: 10.7554/elife.84355.3

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Dynamic compartmentalization of the pro-invasive transcription factor NHR-67 reveals a role for Groucho in regulating a proliferative-invasive cellular switch in C. elegansDOI 10.7554/elife.84355.3Read

A developmental gene regulatory network for invasive differentiation of the <i>C. elegans</i> anchor cellSemantic proximity Read

FOS-1 promotes basement-membrane removal during anchor-cell invasion in C. elegans.Semantic proximity Read

HERD-1 mediates multiphase condensate immiscibility to regulate small RNA-driven transgenerational epigenetic inheritance.Semantic proximity Read

Spatial and molecular cues for cell outgrowth during C. elegans uterine development.Semantic proximity Read

Regulation of gene expression by repression condensates during developmentSemantic proximity Read

Dynamics of a developmental switch: recursive intracellular and intranuclear redistribution of Caenorhabditis elegans POP-1 parallels Wnt-inhibited transcriptional repression.Semantic proximity Read

C. elegans Runx/CBFβ suppresses POP-1 TCF to convert asymmetric to proliferative division of stem cell-like seam cells.Semantic proximity Read

The WAVE/SCAR complex promotes polarized cell movements and actin enrichment in epithelia during C. elegans embryogenesis.Semantic proximity Read

Combinatorial decoding of the invariant C. elegans embryonic lineage in space and time.Semantic proximity Read

Cyclin E and Cdk2 Control GLD-1, the Mitosis/Meiosis Decision, and Germline Stem Cells in Caenorhabditis elegansSemantic proximity Read

Spatiotemporal Gene Expression Analysis of theCaenorhabditis elegansGermline Uncovers a Syncytial Expression SwitchSemantic proximity Read

Trailer Hitch tunes condensate phase behavior and mRNA partitioning to regulate P-body homeostasis during <i>Drosophila melanogaster</i> oogenesisSemantic proximity Read