Article

A developmental gene regulatory network for invasive differentiation of the <i>C. elegans</i> anchor cell

2019-07-03

Abstract excerpt

<h4>ABSTRACT</h4> Cellular invasion is a key part of development, immunity, and disease. Using the in vivo model of C. elegans anchor cell invasion, we characterize the gene regulatory network that promotes invasive differentiation. The anchor cell is initially specified in a stochastic cell fate decision mediated by Notch signaling. Previous research has identified four conserved transcription factors, fos-1a...

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Literature Corpus work: 7e31e436-a145-58ba-b6d4-b47d14359f01
DOI: 10.1101/691337

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