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Article

C. elegans Runx/CBFβ suppresses POP-1 TCF to convert asymmetric to proliferative division of stem cell-like seam cells.

Development (Cambridge, England) - 18 Nov 2019

van der Horst Suzanne E M, Cravo Janine, Woollard Alison, Teapal Juliane, van den Heuvel Sander

Abstract excerpt

A correct balance between proliferative and asymmetric cell divisions underlies normal development, stem cell maintenance and tissue homeostasis. What determines whether cells undergo symmetric or asymmetric cell division is poorly understood. To gain insight into the mechanisms involved, we studied the stem cell-like seam cells in the Caenorhabditis elegans epidermis. Seam cells go through a reproducible pattern...

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Identifiers

PMID: 31740621
DOI: 10.1242/dev.180034
PMCID: PMC6899014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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