Article

X chromosome factor Kdm6a enhances memory independent of its demethylase function in the aging XY male brain

2022-07-19

Abstract excerpt

<h4>ABSTRACT</h4> Males exhibit shorter lifespan and more cognitive deficits in aging human populations. In mammals, the X chromosome is enriched for neural genes and is a major source of biologic sex difference, in part, because males show decreased expression of select X factors. While each sex (XX and XY) harbors one active X due to X chromosome inactivation in females, some genes, such as Kdm6a , transcripti...

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Literature Corpus work: 0cbfbb54-733d-5aef-acfd-b37a2bd602c1
DOI: 10.1101/2022.07.18.500498

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X chromosome factor Kdm6a enhances memory independent of its demethylase function in the aging XY male brainDOI 10.1101/2022.07.18.500498Read

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