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Article

Sexually divergent DNA methylation programs with hippocampal aging

2017-07-10

Abstract excerpt

<h4>Summary</h4> DNA methylation is a central regulator of genome function and altered methylation patterns are indicative of biological aging and mortality. Age-related cellular, biochemical, and molecular changes in the hippocampus lead to cognitive impairments and greater vulnerability to neurodegenerative disease that varies between the sexes. The role of hippocampal epigenomic changes with aging in these pro...

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Literature Corpus work
cf61de6e-c34b-5a5c-b750-0641de2b5e4b
DOI
10.1101/161752
Open publication

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Sexually divergent DNA methylation programs with hippocampal agingDOI 10.1101/161752
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