Article

Experimental menopause in 3xTg-AD mice exacerbates metabolic, inflammatory, and osteologic phenotypes aligned with Alzheimer's disease pathology

2025-10-06

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Alzheimer’s disease (AD) is neurodegenerative disease characterized by the accumulation of amyloid-beta plaques and phosphorylated tau. An estimated 7.2 million Americans are currently living with AD, nearly two-thirds of which are women. Sex differences in AD prevalence and pathology are well established, however the mechanisms underlying these differences are u...

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Literature Corpus work: ac9d9236-8b36-5ff5-b53c-8d1aa20a2eea
DOI: 10.21203/rs.3.rs-7769003/v1

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