Inflammation: Bridging Age, Menopause and APOEε4 Genotype to Alzheimer’s Disease

Abstract excerpt

Neuro-inflammatory processes that contribute to development of Alzheimer's are evident early in the latent prodromal phase and worsen during the course of the disease. Despite substantial mechanistic and clinical evidence of inflammation, therapeutic approaches targeting inflammation have failed to alter the course of the disease. Disparate results from epidemiological and clinical trials targeting inflammation,...

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