Back to search

Article

Long-read isoform sequencing reveals tissue-specific isoform expression between active and hibernating brown bears ( <i>Ursus arctos</i> )

2021-07-14

Abstract excerpt

<h4>Summary</h4> Understanding hibernation in brown bears ( Ursus arctos ) can provide insight into many human diseases. During hibernation, brown bears experience states of insulin resistance, physical inactivity, extreme bradycardia, obesity, and the absence of urine production. These states closely mimic human diseases such as type 2 diabetes, muscle atrophy, renal and heart failure, cachexia, and obesity. Th...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
37a50867-a89c-54e4-852a-e8231728f6b0
DOI
10.1101/2021.07.13.452179
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Long-read isoform sequencing reveals tissue-specific isoform expression between active and hibernating brown bears ( <i>Ursus arctos</i> )DOI 10.1101/2021.07.13.452179
Select a neighboring publication to make it the new centre.