Article

PHF6 maintains acute myeloid leukemia via regulating NF-kB signaling pathway

2022-10-18

Abstract excerpt

<title>Abstract</title> <p>Acute myeloid leukemia (AML) is a major hematopoietic malignancy characterized by the accumulation of immature and abnormally differentiated myeloid cells in bone marrow. Here with <italic>in vivo</italic> and<italic> in vitro </italic>models, we demonstrate that the Plant homeodomain finger gene 6 (PHF6) plays an important role in apoptosis and proliferation in myeloid leukemia. Phf6 d...

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Literature Corpus work: 0c219e4b-da64-5afe-97e4-d35581aadaf8
DOI: 10.21203/rs.3.rs-2095274/v1

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