Article

The Design and Implementation of a Novel Pharmacogenomic Assay to Genotype the CYP3A53 (rs776746) and CYP3A51E (rs4646453) Genetic Variants

2023-04-10

Abstract excerpt

<h4>Background: </h4> The cytochrome P450 3A5 CYP3A5 enzymes are important for metabolizing the drug tacrilomus, an immunosuppressive agent used in solid organ transplantation. Genetic variants in the CYP3A5 gene are significant determinants of tacrolimus efficacy. The present study was undertaken to design a novel pharmacogenetic assay (Single step-Tetra Arms Polymerase Chain Reaction) to study the distribution o...

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Literature Corpus work: 0c17231d-8dc9-5886-acc0-fa459ae9ea42
DOI: 10.21203/rs.3.rs-2651198/v1

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The Design and Implementation of a Novel Pharmacogenomic Assay to Genotype the CYP3A53 (rs776746) and CYP3A51E (rs4646453) Genetic VariantsDOI 10.21203/rs.3.rs-2651198/v1Read

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