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Article

Evaluation of tacrolimus-related CYP3A5 genotyping in China: Results from the First External Quality Assessment Exercise.

Journal of clinical laboratory analysis - 1 Oct 2018

Lin Guigao, Zhang Xiao, Zhang Kuo, Han Yanxi, Tan Liming, Li Jinming

Abstract excerpt

BACKGROUND: Tacrolimus is the most widely used immunosuppressant in solid organ transplant patients. The cytochrome P450 3A5 (CYP3A5) has been proved to be associated with tacrolimus dose requirement. Molecular detection for CYP3A5 genotyping is demanded for the optimization of treatments of tacrolimus. METHODS: To achieve the consistency and accuracy of the testing results, the Chinese National Center for...

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Identifiers

PMID: 29708622
DOI: 10.1002/jcla.22563
PMCID: PMC6817186

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