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Article

A Novel Laboratory-Developed Test Using Multiplex qPCR to Further Personalize Tacrolimus Dosing.

International journal of molecular sciences - 30 Jun 2026

Chadha Abhishek, Wang Zhiwei, Mamroth Max, Hunter John, Xu Lin, Sahoo Sanghamitra, Rumpler Marc, Vlassov Alexandre, Chikova Anna K

Abstract excerpt

Tacrolimus is an immunosuppressant drug commonly used in transplantation. Although multiple studies have demonstrated that polymorphisms in the CYP3A5 gene impact the metabolism of tacrolimus, routine pre-transplant testing for these markers is still not broadly implemented. TacroType™-a new laboratory-developed test implemented by One Lambda Laboratories-utilizes a qPCR-based six-plex assay for CYP3A5 genotyping...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42450184
DOI: 10.3390/ijms27135917
PMCID: PMC13361501

Genes

CYP3A5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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