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Article

Genotyping cytochrome P450 3A5 using the Light Cycler.

Annals of clinical biochemistry - 1 Sept 2005

Fredericks Salim, Moreton Michelle, MacPhee Iain A M, Mohamed Maha, Marlowe Sharon, Jorga AnaMaria, Johnston Atholl, Carter Nicholas D, Holt David W

Abstract excerpt

Cytochrome P450 3A5 (CYP3A5) is involved in the biotransformation of many orally administered drugs, some of which are dose optimized using therapeutic drug monitoring. The CYP3A5 gene exhibits variable inter-individual expression, which is related to a single-nucleotide polymorphism. Producers of the enzyme possess at least one CYP3A5*1 allele. Knowledge of patients' CYP3A5 genotype, in conjunction with...

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Identifiers

PMID: 16168193
DOI: 10.1258/0004563054889927

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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