Article

sctrial: Participant-Level Differential Analysis for Longitudinal Single-Cell Experiments

2026-04-06

Abstract excerpt

<h4>ABSTRACT</h4> Longitudinal single-cell RNA sequencing studies in clinical trials and translational cohorts offer a powerful view of treatment response, disease progression, and cellular dynamics, but their hierarchical structure poses a major inferential challenge: thousands of cells are measured within the same participants across repeated time points, whereas the participant, not the cell, is the true unit...

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Literature Corpus work: 0c083f00-96c2-59fa-bbe4-4dda23b685c1
DOI: 10.64898/2026.04.02.716219

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