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Article

Investigation of transcriptional and immunological disparities among patient groups with varied prognostic risk factors in cholangiocarcinoma.

Cancer medicine - 1 Aug 2024

Zhang Baoluhe, Jin Bao, Wu Xiang'an, Xing Jiali, Liu Xiao, Wan Xueshuai, Xu Haifeng, Xu Yiyao, Mao Yilei, Chen Qian, Bai Yating, Guan Mei, Du Shunda

Abstract excerpt

BACKGROUND: This study explores molecular features associated with better prognosis in cholangiocarcinoma (CCA). METHODS AND RESULTS: The transcriptomic and whole-exome sequencing data obtained from paired tissues of 70 were analyzed, grouping them based on progression-free survival (PFS), differentiation degree, and lymph node metastasis. Among the 70 patients, the TP53 gene mutation frequency was the highest...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39206584
DOI: 10.1002/cam4.70135
PMCID: PMC11358702

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