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Signalling networks in cholangiocarcinoma: Molecular pathogenesis, targeted therapies and drug resistance

23 Mar 2019

Abstract excerpt

Cholangiocarcinoma (CCA) is a deadly disease. While surgery may attain cure in a minor fraction of cases, therapeutic options in either the adjuvant or advanced setting are limited. The possibility of advancing the efficacy of therapeutic approaches to CCA relies on understanding its molecular pathogenesis and developing rational therapies aimed at interfering with oncogenic signalling networks that drive and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30903728
DOI: 10.1111/liv.14102

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