Article

Therapeutic Potential of PRMT1 as a Critical Survival Dependency Target in Multiple Myeloma

2025-02-01

Abstract excerpt

Multiple myeloma (MM) is a neoplasm of antibody-producing plasma cells and is the second most prevalent hematological malignancy worldwide. Development of drug resistance and disease relapse significantly impede the success of MM treatment, highlighting the critical need to discover novel therapeutic targets. In a custom CRISPR/Cas9 screen targeting 197 DNA damage response-related genes, Protein Arginine N-Methylt...

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Literature Corpus work: 037b2849-0724-5851-b04a-d762bd9fd6df
DOI: 10.1101/2025.01.29.635603

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