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Designing Effective Protein Lysine and Arginine Methyltransferase Inhibitors for Chemotherapeutic Targeting

2025-08-07

Abstract excerpt

Standard cancer chemotherapy is increasingly being supplemented with novel therapeutics to overcome known chemoresistance pathways. Resistance to treatment is common across various tumor types, driven by multiple mechanisms. One emerging contributor is protein methylation, a post-translational modification mediated by protein methyltransferases (PMTs), which regulate protein function by adding methyl groups, mainl...

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Literature Corpus work
618bbfee-537e-53d4-b95b-9c79159bff64
DOI
10.20944/preprints202508.0391.v1
Open publication

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Designing Effective Protein Lysine and Arginine Methyltransferase Inhibitors for Chemotherapeutic TargetingDOI 10.20944/preprints202508.0391.v1
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