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Article

CYP2A6 is associated with obesity: studies in human samples and a high fat diet mouse model.

International journal of obesity (2005) - 1 Mar 2019

Wang Kesheng, Chen Xue, Ward Stephen C, Liu Ying, Ouedraogo Youssoufou, Xu Chun, Cederbaum Arthur I, Lu Yongke

Abstract excerpt

BACKGROUND/OBJECTIVES: CYP2A6 (CYP2A5 in mice) is mainly expressed in the liver. Hepatic CYP2A6 expression is increased in patients with non-alcoholic fatty liver disease (NAFLD). In mice, hepatic CYP2A5 is induced by high fat diet (HFD) feeding. Hepatic CYP2A5 is also increased in monosodium glutamate-induced obese mice. NAFLD is associated with obesity. In this study, we examined whether obesity is related to...

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Identifiers

PMID: 29568101
DOI: 10.1038/s41366-018-0037-x
PMCID: PMC6102101

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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