Article
Characterization of metabolic phenotypes of mice lacking GPR61, an orphan G-protein coupled receptor.
Life sciences - 21 Nov 2011
Nambu Hirohide, Fukushima Miyuki, Hikichi Hirohiko, Inoue Takao, Nagano Norihiro, Tahara Yoshio, Nambu Tadahiro, Ito Junko, Ogawa Yoshihiro, Ozaki Satoshi, Ohta Hisashi
Abstract excerpt
AIMS: GPR61 is an orphan G protein-coupled receptor whose function remains unknown. The purpose of the present study is to elucidate the importance of GPR61 in metabolism by characterization of GPR61-deficient mice. MAIN METHODS: Male GPR61-deficient mice were characterized regarding various metabolic parameters, including food intake, body weight, oxygen consumption, body temperature, locomotor activity, and in...
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