Article

Melatonin ameliorates neurological deficits through MT2/IL-33/ferritin H signaling-mediated inhibition of neuroinflammation and ferroptosis after traumatic brain injury

2023-01-04

Abstract excerpt

<title>Abstract</title> <p>Although traumatic brain injury (TBI) is a common cause of death and disability worldwide, there is currently a lack of effective therapeutic drugs or targets. To reveal the complex pathophysiologic mechanisms of TBI, we performed transcriptome analysis of the mouse cerebral cortex and immunohistochemical analysis of human cerebral tissues. The genes <italic>Mt1, Mt2, Il33, and Fth1</it...

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Literature Corpus work: 0b8b6462-5176-5534-a095-83ffd275d633
DOI: 10.21203/rs.3.rs-2383078/v1

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