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Article

Ferrostatin-1 Polarizes Microglial Cells Toward M2 Phenotype to Alleviate Inflammation After Intracerebral Hemorrhage.

Neurocritical care - 1 Jun 2022

Huang Lijuan, Zhang Yanjiao, Zhao Liang, Chen Qingyou, Li Li

Abstract excerpt

BACKGROUND: Intracerebral hemorrhage (ICH) is one of the most lethal stroke types and lacks effective therapeutic regimens. Recently, evidence has suggested the involvement of the ferroptosis inhibitor ferrostatin-1 (Fer-1) in the pathophysiological process of ICH. In this study, we examined the underlying mechanism. METHODS: We induced an in vitro apoptosis model in organotypic hippocampal slice (OHS) using...

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PMID: 35099711
DOI: 10.1007/s12028-021-01401-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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