Article

Neutrophil extracellular traps promote neuronal ferroptosis through STING-mediated AMPK dysregulation after traumatic brain injury

2026-01-06

Abstract excerpt

<title>Abstract</title> <p>Neuronal ferroptosis exacerbates neurological dysfunction after traumatic brain injury (TBI), yet the upstream signals driving this process remain poorly defined. Here, we identify neutrophil extracellular traps (NETs) as critical mediators of post-TBI ferroptotic injury. In patients, NET accumulation closely accompanied markers of neuronal ferroptosis and correlated with neurological s...

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Literature Corpus work: 9752c7d3-ec85-5652-a862-da9f4ccc20a4
DOI: 10.21203/rs.3.rs-8482248/v1

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