Article

MS-driven metabolic alterations are recapitulated in iPSC-derived astrocytes

2021-08-28

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Astrocytes play a significant role in the pathology of Multiple Sclerosis (MS). Nevertheless, for ethical reasons, most of the studies in these cells were performed on the Experimental Autoimmune Encephalomyelitis model. As there are significant differences between human and mouse cells, we aimed here to better characterize astrocytes from patients with MS (PwMS), focusing ma...

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Literature Corpus work: 0b8266b4-2bfd-5fd5-a5ee-a66f9c320b13
DOI: 10.1101/2021.08.27.457853

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