Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic and Mitochondrial Metabolic Dysfunction in Multiple Sclerosis: A Review of Herbal Drug Approaches and Current Clinical Trials

3 Apr 2025

Abstract excerpt

Multiple sclerosis (MS) is a complex autoimmune disease characterised by inflammation, demyelination, and neurodegeneration within the central nervous system (CNS). While the exact causes remain unclear, recent research highlights the significant role of epigenetic modifications and mitochondrial dysfunction in the disease's onset and progression. Epigenetic alterations, such as DNA methylation, histone...

Topics

Join the communities discussing this publication.

MicroRNA in disease regulation
Multiple Sclerosis Research Studies
Neuroinflammation and Neurodegeneration Mechanisms

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 40180689
DOI: 10.1007/s12035-025-04868-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic and Mitochondrial Metabolic Dysfunction in Multiple Sclerosis: A Review of Herbal Drug Approaches and Current Clinical TrialsPMID 40180689Read ↗

Integrating Lipidomics and Transcriptomics Reveals the Crosstalk Between Oxidative Stress and Neuroinflammation in Central Nervous System DemyelinationSemantic proximity Read ↗

Mitochondrial and metabolic dysfunction of peripheral immune cells in multiple sclerosisSemantic proximity Read ↗

Aberrant DNA methylation profile exacerbates inflammation and neurodegeneration in multiple sclerosis patientsSemantic proximity Read ↗

Decoding the molecular and cellular aspects of multiple sclerosis: From diagnosis to therapeutic strategiesSemantic proximity Read ↗

Epigenetics and miRNAs in the diagnosis and treatment of multiple sclerosisSemantic proximity Read ↗

Common Pathophysiological Molecular Mechanisms Shared Between the Pathogenesis of Obesity and Multiple Sclerosis and the Effects of Various Antioxidant Compounds as Complementary Therapy for Multiple Sclerosis: A Comprehensive ReviewSemantic proximity Read ↗

Mitochondrial Dysfunction and Multiple SclerosisSemantic proximity Read ↗

Epigenetic mechanisms in multiple sclerosis: implications for pathogenesis and treatmentSemantic proximity Read ↗

MS-driven metabolic alterations are recapitulated in iPSC-derived astrocytesSemantic proximity Read ↗

Patients with multiple sclerosis show increased oxidative stress markers and somatic telomere length shorteningSemantic proximity Read ↗

Multiple Sclerosis: Lipids, Lymphocytes, and Vitamin DSemantic proximity Read ↗

Significance of Mitochondrial Dysfunction in the Progression of Multiple SclerosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.