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Article

ZNF574 is a Quality Control Factor For Defective Ribosome Biogenesis Intermediates

2024-04-29

Abstract excerpt

Eukaryotic ribosome assembly is an intricate process that involves four ribosomal RNAs, 80 ribosomal proteins, and over 200 biogenesis factors that take part in numerous interdependent steps. This complexity creates a large genetic space in which pathogenic mutations can occur. Dead-end ribosome intermediates that result from biogenesis errors are rapidly degraded, affirming the existence of quality control pathwa...

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Literature Corpus work
0b7d32d3-949d-5679-86d4-2d22115114c1
DOI
10.1101/2024.04.26.591394
Open publication

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ZNF574 is a Quality Control Factor For Defective Ribosome Biogenesis IntermediatesDOI 10.1101/2024.04.26.591394
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