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Eukaryotic ribosome quality control system: a potential therapeutic target for human diseases

1 Jan 2022

Abstract excerpt

Protein homeostasis is well accepted as the prerequisite for proper operation of various life activities. As the main apparatus of protein translation, ribosomes play an indispensable role in the maintenance of protein homeostasis. Nevertheless, upon stimulation of various internal and external factors, malfunction of ribosomes may be evident with the excessive production of aberrant proteins, accumulation of...

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PMID: 35414791
DOI: 10.7150/ijbs.70955

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