Article
MicroRNAs and long non-coding RNAs as novel regulators of ribosome biogenesis.
Biochemical Society transactions - 29 Apr 2020
McCool Mason A, Bryant Carson J, Baserga Susan J
Abstract excerpt
Ribosome biogenesis is the fine-tuned, essential process that generates mature ribosomal subunits and ultimately enables all protein synthesis within a cell. Novel regulators of ribosome biogenesis continue to be discovered in higher eukaryotes. While many known regulatory factors are proteins or small nucleolar ribonucleoproteins, microRNAs (miRNAs), and long non-coding RNAs (lncRNAs) are emerging as a novel...
Topics
- Cell Nucleolus
- Computational Biology
- Gene Expression Regulation, Neoplastic
- Humans
- MicroRNAs
- Neoplasms
- Phenotype
- RNA, Long Noncoding
- RNA, Ribosomal, 5S
- Ribonucleoproteins, Small Nucleolar
- Ribosomal Proteins
