Back to search

Article

Ligand Effects on Phase Separation of Multivalent Macromolecules

2020-08-15

Abstract excerpt

Biomolecular condensates enable spatial and temporal control over cellular processes by concentrating biomolecules into non-stoichiometric assemblies. Many condensates form via reversible phase transitions of condensate-specific multivalent macromolecules known as scaffolds. Phase transitions of scaffolds can be regulated by changing the concentrations of ligands, which are defined as non-scaffold molecules that b...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
da3932d2-6081-5da3-aecb-7e7e7536a09f
DOI
10.1101/2020.08.15.252346
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Ligand Effects on Phase Separation of Multivalent MacromoleculesDOI 10.1101/2020.08.15.252346
Controlled and orthogonal partitioning of large particles into biomolecular condensatesSemantic proximity
Biomolecular Condensates Decipher Molecular Codes of Cell Fate: From Biophysical Fundamentals to Therapeutic Practices.Semantic proximity
DNA Partitioning Modulates Liquid-to-Solid Transitions and the Internal Microstructure of FUS CondensatesSemantic proximity
Mechano-dependent sorbitol accumulation supports biomolecular condensateSemantic proximity
Compartmentalization of telomeres through DNA-scaffolded phase separationSemantic proximity
OptoChaperone – A biohybrid tool for regulating protein condensates in cells and <i>in vitro</i>Semantic proximity
A Comprehensive Mathematical Model of Avidity in Cytokine SignalingSemantic proximity
Phase-Separated Transcriptional Condensates Accelerate Target-Search Process Revealed by Live-Cell Single-Molecule Imaging.Semantic proximity
Merging Established Mechanisms with New Insights: Condensates, Hubs, and the Regulation of RNA Polymerase II Transcription.Semantic proximity
Investigating the Context-Dependent Phase Separation of Human HOX Transcription FactorsSemantic proximity
Rules for hardening influenza A virus liquid condensatesSemantic proximity
Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutions.Semantic proximity
Select a neighboring publication to make it the new centre.