Article

Large-scale genetic screens identify BET-1 as a cytoskeleton regulator promoting actin health and lifespan

2022-06-22

Abstract excerpt

The actin cytoskeleton is a three-dimensional scaffold of proteins that is a regulatory, energy-consuming network with dynamic properties to shape the structure and function of the cell. Proper actin function is required for many cellular pathways, including cell division, autophagy, chaperone function, endocytosis, and exocytosis. Deterioration of these processes manifests during aging and exposure to stress, whi...

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Literature Corpus work: 0b6a8565-9fe3-53b8-9805-1a76821450ca
DOI: 10.1101/2022.06.22.497249

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