Article
Regulators of the actin cytoskeleton mediate lethality in a Caenorhabditis elegans dhc-1 mutant.
Molecular biology of the cell - 1 Aug 2010
Gil-Krzewska Aleksandra J, Farber Erica, Buttner Edgar A, Hunter Craig P
Abstract excerpt
Functional analysis of cytoplasmic dynein in Caenorhabditis elegans has revealed a wide range of cellular functions for this minus-end-directed motor protein. Dynein transports a variety of cargos to diverse cellular locations, and thus cargo selection and destination are likely regulated by accessory proteins. The microtubule-associated proteins LIS-1 and dynein interact, but the nature of this interaction...
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