Article
Transcriptome analysis of adult Caenorhabditis elegans cells reveals tissue-specific gene and isoform expression.
PLoS genetics - 1 Aug 2018
Kaletsky Rachel, Yao Victoria, Williams April, Runnels Alexi M, Tadych Alicja, Zhou Shiyi, Troyanskaya Olga G, Murphy Coleen T
Abstract excerpt
The biology and behavior of adults differ substantially from those of developing animals, and cell-specific information is critical for deciphering the biology of multicellular animals. Thus, adult tissue-specific transcriptomic data are critical for understanding molecular mechanisms that control their phenotypes. We used adult cell-specific isolation to identify the transcriptomes of C. elegans' four major...
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