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Article

Form and function of actin impacts actin health and aging

2025-11-23

Abstract excerpt

The actin cytoskeleton is a fundamental and highly conserved structure that functions in diverse cellular processes, yet its direct contribution to organismal aging remains unclear. Here, we systematically interrogated how genetic and pharmacologic perturbations of actin structure and function influence lifespan and various hallmarks of aging in Caenorhabditis elegans . Whole-animal and tissue-specific knockdown...

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Identifiers and source

Literature Corpus work
05a71b06-570e-5c7f-8b1e-f6ab537b6bcf
DOI
10.1101/2025.11.22.689949
Open publication

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Form and function of actin impacts actin health and agingDOI 10.1101/2025.11.22.689949
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