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Investigation of imprinted differentially methylated regions implicates placenta- specific haplotypes as potential internal reference markers for non-invasive prenatal testing

2023-09-22

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Imprinted genes play important roles in placental development and fetal growth. The human placenta exhibits a unique pattern in genomic imprinting compared to that in somatic tissues. Here, we investigated imprinted differentially methylated regions (iDMRs) in the placenta and their changes associated with preeclampsia. <bold>Methods:</bold> We analyzed 3362 CpG...

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Literature Corpus work: 0b32fcee-07fb-5542-aa3c-9eb82cddc717
DOI: 10.21203/rs.3.rs-3354615/v1

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